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About The Study | PERSIANLineageCohort Home Site Mape Contact Us   PERSIANLineageCohort Previous Pause Next About The StudyBackground Vision Goal Objective About UsOrganization Project Management International partnerships ResearchProtocol Conceptual framework Study setting Data hodgepodge Health determinants & outcomes Data hodgepodge methods Data hodgepodge in Phase 1 Data hodgepodge in Phase 2 Quality tenancy Ethical considerations Study Questionnaires NewsNews Steering Committee Meetings The PBC Gallery Related LinksPERSIANLineageCohort PERSIAN Cohort InternationalLineageCohorts Contact Us About The Study Background Vision Goal Objectives Background: During the past decades, as a result of largest tenancy of vitiating diseases and achieving higher life expectancy, the global disease undersong has unfurled to shift yonder from vitiating to non-communicable diseases which now contribute to a major part of disability-adjusted life years (DALYs) and mortality worldwide . Similarly, in Iran, there has been an increase in prevalence of chronic non-communicable diseases and their contribution to morbidity and mortality during recent years and this trend is expected to protract in coming years. Taking into worth the considerable individual and societal undersong twin these conditions, interventions targeted at preventing these conditions have increasingly wilt a top priority for the Iranian health system. Developmental Origins of Health and Diseases (DOHaD) has provided new insight towards novel ways of tackling non-communicable diseases by interventions aimed at conditions early in life. To date, however, little has been washed-up with regards to such interventions in Iran, partly considering of lack of local vestige for the effects of early life conditions on non-communicable diseases in adulthood. Furthermore, a growing soul of vestige has associated pre and postnatal conditions with neurodevelopment in children. Therefore, interventions aiming at improving such early life conditions could result in an wholesomeness in population mental capital, which in turn would have lasting effects through the life-course.Consideringof contextual and cultural differences, the findings of studies dealing with DOHaD that are mostly conducted in Western ripened countries are not necessarily generalizable to the Iranian population. Our proposed project will be based on a multi-centre nationally-representative lineage cohort to study DOHaD in Iranian population taking local contextual and cultural aspects into account. The findings of this project will not only inform policymakers regarding evidence-based interventions targeted at Iranian population, but moreover will enable Iran to wilt one of the pioneers of DOHaD research worldwide. Vision: The study vision is to establish a robust and flexible framework to self-mastery world-class cutting-edge studies on not only existing health challenges of the Iranian population, but moreover on challenges that might sally in future. Goal: The overarching aim of this project is to study Developmental Origins of Health and Diseases (DOHaD) in Iranian population. Towards this aim, we will evaluate the impact of socioenvironmental, psychological and genetic factors on pregnancy outcomes, child mental and physical health, growth, and development, and early- and late-onset chronic non-communicable diseases. Objectives: Establishing an integrated multi-centre network of population-based lineage cohorts in areas representing cultural and contextual variations in Iran. Developing standardised protocols for data collection, maintenance, and wringer tailored for Iranian population with the prospect of future international collaborations. Recruiting the participants, collecting the data, managing, cleaning, and harmonizing placid data and maintaining placid bio-samples. Conducting a pilot study to evaluate feasibility, required time and resources, and the potential for unexpected practical issues, and improving project protocol accordingly. Continuing stuff training and quality tenancy throughout the project. Educating a new generation of high-calibre MSc and PhD students wideness variegated disciplines covered by the project. Establishing an interdisciplinary network of in-house and international scientists tent variegated aspects of this multidisciplinary project to identify knowledge gaps and research priorities, provide translating on scientific aspects of the project, and evaluate the progress of the project. Disseminating the results in scientific polity and translating and communicating the findings with unstipulated public as well as interested stakeholders including policymakers. Quick Link About The Study About Us Research News FAQ Related Links Contact Us Contact: Email: info@persian-bc.family © Copyright 2016-2018 by PERSIANLineageCohort. All Rights Reserved. Design By NiCOMP.ir